Pizza Hut Pepperoni Lover's Pizza, Medium Hand Tossed (1 slice): 280 calories
- 12gProtein
- 26gCarbs
- 14gFat
- 570mgSodium
Add it to an order in the calculator
Official U.S. values from Pizza Hut Nutrition Information (U.S.), last checked October 25, 2026. Restaurants change recipes, so values in your area can differ.
Pizza Hut Pepperoni Lover's Pizza, Medium Hand Tossed nutrition facts
| Item | Calories | Protein | Carbs | Fat | Sodium | Sat. fat | Sugar | Fiber | % of 2,000 cal |
|---|---|---|---|---|---|---|---|---|---|
| Pepperoni Lover's Pizza, Medium Hand Tossed (1 slice) | 280 | 12g | 26g | 14g | 570mg | 6g | 2g | 1g | 14% |
The Pizza Hut Pepperoni Lover's Pizza, Medium Hand Tossed (1 slice) is about 14% of a 2,000-calorie day and 25% of the 2,300mg daily sodium limit in the U.S. Dietary Guidelines.
How the Pepperoni Lover's Pizza, Medium Hand Tossed ranks
- The Pepperoni Lover's Pizza, Medium Hand Tossed (1 slice) is the 2nd highest in calories of the 11 items in the Pizza Hut “Hand Tossed Pizza (Medium, per slice)” menu, and 2nd for protein per calorie.
- Across the 57 items of the same kind we track at 3 chains, it is the 25th highest in calories; their average is 279 calories.
How to make a Pizza Hut order lighter
- Order the Cheese Pizza, Medium Hand Tossed (1 slice) instead: 60 fewer calories, 10g protein.
- Order the Pepperoni Pizza, Medium Hand Tossed (1 slice) instead: 50 fewer calories, 9g protein.
- Order the Double Pepperoni Pizza, Medium Hand Tossed (1 slice) instead: 50 fewer calories, 9g protein.
How long it takes to burn off
For a 155 lb person, the Pizza Hut Pepperoni Lover's Pizza, Medium Hand Tossed (1 slice) takes about 63 minutes of brisk walking, 29 minutes of running (5 mph) or 29 minutes of cycling. Figures from Harvard Health’s calories-burned table; heavier people burn calories faster.
Compared with other restaurants
Similar-calorie pizza slices at other chains (same size where the chain has one):
- Domino's Cheese Pizza (1 slice): 285 calories, 11g protein
- Taco Bell Veggie Mexican Pizza: 460 calories, 14g protein
Questions people ask
The Pizza Hut Pepperoni Lover's Pizza, Medium Hand Tossed (1 slice) has 280 calories, with 12g of protein, 26g of carbs and 14g of fat, according to the restaurant’s official U.S. nutrition information.
The Cheese Pizza, Medium Hand Tossed (1 slice) has 220 calories, 60 fewer, and still keeps most of the protein.
More Pizza Hut calories
Cheese Pizza, Medium Original Pan · Pepperoni Pizza, Medium Original Pan · Supreme Pizza, Medium Original Pan · Meat Lover's Pizza, Medium Original Pan · Backyard BBQ Chicken Pizza, Medium Original Pan · Chicken Sausage & Bacon Classic Pizza, Medium Original Pan · Double Pepperoni Pizza, Medium Original Pan · Pepperoni Lover's Pizza, Medium Original Pan · Pesto Margherita Pizza, Medium Original Pan · The Ultimate Pizza, Medium Original Pan · Veggie Lover's Pizza, Medium Original Pan · Cheese Pizza, Medium Hand Tossed · Pepperoni Pizza, Medium Hand Tossed · Supreme Pizza, Medium Hand Tossed · Backyard BBQ Chicken Pizza, Medium Hand Tossed · Chicken Sausage & Bacon Classic Pizza, Medium Hand Tossed · Double Pepperoni Pizza, Medium Hand Tossed · Meat Lover's Pizza, Medium Hand Tossed · Pesto Margherita Pizza, Medium Hand Tossed · The Ultimate Pizza, Medium Hand Tossed · Veggie Lover's Pizza, Medium Hand Tossed · Cheese Pizza, Medium Thin 'N Crispy · Pepperoni Pizza, Medium Thin 'N Crispy · Backyard BBQ Chicken Pizza, Medium Thin 'N Crispy · Chicken Sausage & Bacon Classic Pizza, Medium Thin 'N Crispy · Double Pepperoni Pizza, Medium Thin 'N Crispy · Meat Lover's Pizza, Medium Thin 'N Crispy · Pepperoni Lover's Pizza, Medium Thin 'N Crispy · Pesto Margherita Pizza, Medium Thin 'N Crispy · Supreme Pizza, Medium Thin 'N Crispy · The Ultimate Pizza, Medium Thin 'N Crispy · Veggie Lover's Pizza, Medium Thin 'N Crispy · Cheese Pizza, Medium Original Stuffed Crust · Pepperoni Pizza, Medium Original Stuffed Crust · Supreme Pizza, Medium Original Stuffed Crust · Meat Lover's Pizza, Medium Original Stuffed Crust · Veggie Lover's Pizza, Medium Original Stuffed Crust · Backyard BBQ Chicken Pizza, Medium Original Stuffed Crust · Chicken-Bacon Parmesan Pizza, Medium Original Stuffed Crust · Breadstick · Cheese Breadstick · Garlic Bread · Fries with Ketchup · Cheesy Dip 'N Chips · Stuffed Pizza Roller · Pepperoni Lover's Melt · Meat Lover's Melt · Chicken Bacon Parmesan Melt · Burger Melt · Oven-Baked Chicken Alfredo Pasta · Oven-Baked Cheesy Alfredo Pasta · Oven-Baked Italian Meats Pasta · Oven-Baked Veggie Pasta · Oven-Baked Triple Cheese Mac · Ultimate Chocolate Chip Cookie · Triple Chocolate Brownie · Chocolate Donut Bites